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Screening for Biological Response Modifiers: Methods and Rationale by James E. T

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Procedures for Preclinical Screening of Biological Response Modifying Agents. Preclinical Evaluation of Individual Biological Response Modifiers. Clinical Correlations. To aid in the search for these new chemicals and to attempt to distinguish among the many toxic chemicals which might be candidates for clinical studies, the National Cancer Institute, the pharmaceutical industry, and the cancer research laboratories of most Western nations developed systems for "screening" drugs for antitumor activity.

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